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ACID SENSING ION CHANNELS
Descriptors Found:
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DeCS
Descriptor
English
:
Acid Sensing Ion Channels
Descriptor
Spanish
:
Canales Iónicos Sensibles al Ácido
Descriptor
Portuguese
:
Canais Iônicos Sensíveis a Ácido
Synonyms
English
:
ASIC Channel
Acid-Sensing Ion Channels
Proton Gated Sodium Channels
Proton-Gated Sodium Channels
Sodium Channels, Proton-Gated
Tree Number:
D12.776.157.530.400.875.050
D12.776.543.550.450.875.050
D12.776.543.585.400.875.050
D12.776.631.024
Definition
English
:
A
family
of proton-gated
sodium channels
that are primarily expressed in neuronal
tissue
. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions.
Entry Combination - descr/qualif
English
:
Acid Sensing Ion Channels
/
antagonists & inhibitors
use
Acid Sensing Ion Channel Blockers
Acid Sensing Ion Channels
/
agonists
use
Sodium Channel Agonists
History Note
English
:
2013
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54944
Unique Identifier:
D062565
Occurrence in VHL
:
Similar:
DeCS